Stem Cell Mobilization
In the past, a bone marrow harvest (a surgical procedure) was the only way to collect stem cells for a transplant. Today it is now possible to collect stem cells from the peripheral blood (from the bloodstream), a process that is easier on you and generally preferred.
If you donate your own stem cells for use in transplant, it is referred to as an autologous stem cell transplant. In order to undergo an autologous transplant, you must have enough stem cells collected to proceed to transplant.
Stem cell mobilization is a process whereby stem cells are stimulated out of the bone marrow space (e.g., the hip bones and the chest bone) into the bloodstream, so they are available for collection for future reinfusion. The cells are then preserved, frozen and stored until the time of transplant.
Some preferred characteristics of a mobilization regimen include:
In addition to Mozobil, other mobilization strategies include growth factor alone or chemotherapy followed by growth factor.